One Case of Autopsy Pathological Analysis of Acute Pancreatitis Combined with Hemorrhage in Pericardial Cavity

Source:
By:Na Tan, Hong Zheng, Jinjing Wang, Ying Cha, Jiajia Huang, Xiaorong Yang, Xinglong Wu

DOI: https://doi.org/10.30564/jams.v1i3.59

Abstract: Senile male, physically ft at usual, he died suddenly without any clinical symptoms. By autopsy dissection, it was found that large amount of bleeding was presented in pericardial cavity, the abdominal cavity and thoracic cavity had a small amount of hemorrhage, partial pancrea tissue had coagulation necrosis accompanied with infltration of neutrophile granulocyte and degeneration and necrosis of liver cell accompanied with acute or chronic inflammation cell infltration. Laboratory examination of the patient when he was alive suggested that liver function and coagulation function had obstacles, there was not any timely clinical process, and he died suddenly. Autopsy examination results suggested that acute pancreatitis caused a large quantity of bleeding in pericardial cavity, which led to cardiac tamponade and it cause acute circulation failure, which initiated cardiac arrest and then death. Coronary heart disease may exert certain facilitation effect in the death process. Patients with pancreatitis, especially the senile and pancreatitis patients with coronary artery disease, should be evaluated and prevented ahead of schedule, for those patients who had coma suddenly, it should be thought that it had possibility of combining with hemorrhage in the interior of pericardial cavity, the patient's doctor should try his or her best to reduce death rate.

References:

[1] Sawlani V, Phadke RV, Baijal SS, et al. Arterial Complications of Pancreatitis and Their Radiological Management[J]. Australia Radiol, 1996, 40(4):381-386. [2] Ziqin Zhao. Legal Medicine Pathology[M]. Beijing: People's Medicine Publishing House, 2004, 398-399. (in Chinese) [3] Qunhua Zhang, Quanxing Ni, Duan Cai. Chinese Medical Journal [J] 2001:114 (7) 738-742. (in Chinese) [4] Aijun Han, Deping He, Hongying Wu, Journal of Clinical Hepatology[J] June 2004, Vol. 20, issue 3. (in Chinese) [5] Xinjing Yang, Jun Wang, Jianhong Fu, et al, Chinese Journal of Critical Care Medicine[J] September 2012, Vol. 32,issue 9. (in Chinese) [6] Yongfeng Fu, Analysis on clinical value of CRP and PCT in evaluation of severity and prognosis factors of acute pancreatitis [D]. North China University of Science and Technology,2015. (in Chinese) [7] Huajing Ke. Clinical Study of Large Dose of Short Term Glucocorticoid Treating concurrent Inflammation Reaction Symptoms of Acute Pancreatitis [D].Nanchang University,2015. (in Chinese) [8] Peiwen Zhu. TCM Discrimination Four-step Therapy Treating Acute Pancreatitis and Its Effect on Serum TN F-α, IL-8 and ICAM-1[D].Henan University of TCM,2015. (in Chinese)