Analysis of the Association between Intestinal Microflora and Long-lived Elderly People
Source: By:Zhilu Li, Ligong Zeng, Zhiwei Zhang, Jixuan Yao, Ruyi Zhang, Zeyang Wu, Zihan Wang, Jianping Zhang, Pingping Yan
DOI: https://doi.org/10.30564/jams.v5i1.3769
Abstract:The intestinal microbiota is the cornerstone of the human intestinal microecosystem and plays an unnegligible role in the growth and health maintenance of the human body. In recent years, many studies have been committed to exploring the potential connection of gut flora and the elderly population. The changes of gut flora are affected by various factors such as age increase, disease, medication, living habits, nutritional structure, and the intestinal flora is expected to be applied to the comprehensive evaluation of elderly health and longevity in the future. Based on this, the research progress of the general elderly and its related influencing factors.
References:[1] Kundu, P., Blacher, E., Elinav, E., et al., 2017. Our gut microbiome: the evolving innerself.Cell. 171(7), 1481-1493. [2] Arumugam, M., Raes, J., Pelletier, E., et al., 2011. Entero types of the human gut microbiome. Nature. 506(7489), 516. [3] Biagi, E., Franceschi, C., Rampelli, S., et al., 2016. Gut microbiota and extreme longevity. Current Biology. 26(11), 1480-1485. [4] Jeffery, I.B., Lynch, D.B., 2016. Oposition and temporal stability of the gut microbiota in older persons. Isme Journal. 10(1), 170. [5] Claesson, M.J., Cusack, S.O., et al., 2011. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. ProcNatlAcad Sci USA. 108(Suppl1), 4586-4591. [6] Ananthaswamy, A., 2011. Faecal transplant eases symptoms of Parkinson. New Scientist. 209(2796), 8-9. [7] Zeng Yi, 2011. Interdisciplinary Studies of Health Impact Factors on Aging. Scientific Bulletin. 56(35), 2929-2940. [8] Claesson, M.J., Jeffery, I.B., Conde, S., et al., 2012. Gut microbiota composition correlates with diet and health in the elderly. Nature. 488(7410), 178-184. DOI: https://doi.org/10. 1038/nature11319. [9] La, D., CF M, RN C, et al., 2014. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 505(7484), 559. [10] Han Xiaoyun, Deng Hong, Cai Yan, et al., 2009. Intestinal Microbiology and Chronic Diseases. Chinese Journal of MicroEcology. 21(11), 1039-1042. [11] Jackson, M.A., Jeffery, I.B., Beaumont, M., et al., 2016. Signatures of early frailty in the gut microbiota. Genome Medicine. 8(1), 8. [12] Li Lanjuan, 2009. Progress in infection microecology — Impact of intestinal microbiota on body metabolism. Chinese Journal of MicroEcology. 21. [13] Kamo, T., Akazawa, H., Suzuki, J., et al., 2017. Novel concept of a heart-gut axis in the pathophysiology of heart failure. Korean Circulation Journal. 47(5), 663-669. [14] Li, J., Zhao, F., Wang, Y., et al., 2017. Gut microbiotadysbiosis contributes to the development of hypertension. Microbiome. 5(1), 14. [15] Qin, J., Li, Y., Cai, Z., et al., 2012. A metagenome-wide association study of gut microbiotain type2 diabetes.Nature. 490(7418), 55-60.. [16] Jie, Z., Xia, H., Zhong, S.L., et al., 2017. The gut microbiome in atherosclerotic cardiovascular disease. Nature Commun. 8(1), 1-12. [17] Ticinesi, A., Lauretani, F., Milani, C., et al., 2017. Aging gut microbiota at the cross-road between nutrition, physical frailty, and sarcopenia:isthereagut-muscle axis? Nutrients. 9(12), 1303. [18] Zhao, L.P., Zhang, Ch.Y., 2010. Obesity-related structural dynamics and functional analysis of gut microbial communities. Life Sciences. 22(12), 1247-1251. [19] Clarke, S.F., Murphy, E.F.O., et al., 2014. Exercise and associated dietary extremes impact on gut microbial diversity. Gut. 63(12), 1913-1920. [20] Cristina, B., Julio, F.G., Leo, P., et al., 2016. Effect of aprebiotic formulation on frailty syndrome: a randomized, double-blind clinical trial. IntJ MolSci. 17(6), 932. [21] Young, V.B., Hayden, M.K., 2016. Environmental management in the gut: fecal transplantation to restore the intestinal ecosystem. Infectious Diseases. 48 (8), 593-595.