Determination of the Administration Routes, Doses and Appropriate Age to Vaccinate With Ornitin Triple Vaccine For Cross-breed Colored Broilers in Vietnam
Source: By:Nguyen Manh Ho, Bui Ngoc Xuan Ha, Le Thi Kim Tuyen, Le Thi Anh Thu, Le Thanh Hien, Quach Tuyet Anh
DOI: https://doi.org/10.30564/vsr.v1i2.1190
Abstract:The study was to determine the appropriate dose and administration route of Ornitin Triple vaccine in cross-breed coloured broilers in Vietnam by evaluating the antibody titer against Ornithobacterium rhinotracheale (ORT) and local reactions at injection sites on chickens after vaccination. The study was divided into 2 trials. Both trials were designed with 3 vaccine dose groups: 0.0ml (control group), 0.25ml and 0.5ml and 2 different administration routes: subcutaneous at neck (SC) and intramuscular at breast (IM) injection. The result showed that, no statistically significant difference was found between antibody titer of two administration routes as well as 2 vaccine doses until 13-week-old. Local reactions at the injection sites of IM route was less severe than SC at neck and in higher dose would produce a more severe swelling reaction. Daily weight gain was found to have a slight decrease in the vaccinated groups within 2 weeks after vaccination, however, no statistically significant difference was found in later stage (P > 0.05). In conclusion, Ornitin Triple can be used to vaccinate by IM with the dose of 0.25ml for coloured broilers at early age (3-week-old), or 0.5ml for older birds and should be careful for some reactions at the injection sites.
References:[1] Bermudez, A. J.. Principles of disease prevention: Diagnosis and Control. Diseases of poultry (12nd ed). Blackwell publishing Press, Ames, Iowa, 2008. [2] Cauwerts, K., De, H. P., Haesebrouck, F., Vervloesem, I., & Ducatelle, R.. The effect of Ornithobacterium rhinotracheale vaccination of broiler breeder chickens on the performance of their progeny. Avian Pathology, 2002, 31(6): 619-624. [3] Chin R. P, Van Empel P.C.M. and Hafez H.M.. Ornithobacterium rhinotracheale Infection. Y. M. Saif. Diseases of Poultry. Lowa State University Press, Ames, Iowa, 2003: 683-690 [4] Chin, R.P., M. v.E.P.C., & M. H.H.. Diseases of poultry. 12ed. Blackwell Publishing Ltd, Oxford, United Kingdom, 2008. [5] Chin, R. P., van Empel P. C. M., & Hafez, H. M.. Ornithobacterium rhinotracheale infection. Saif, Y. M., Fadly A. M., Glisson, J. R., McDougald, L.R., Nolan L.K., and Swayne D. E. (eds.). Diseases of poultry. Oxford, United Kingdom: Blackwell Publishing Ltd, 2013,12th ed.: 765-774. [6] Devriese, L. A., De Herdt, P., & Haesebrouck, F.. Antibiotic sensitivity and resistance in Ornithobacterium rhinotracheale strains from Belgian broiler chickens. Avian Pathology, 2001, 30: 197–200. [7] Hafez, H. M., Vandamme, P. In: Bergey’s Manual of Systematic Bacteriology, Volume 4. 2. Krieg NR, Staley JT, Brown DR, Hedlund BP, Paster BJ, Ward NL, Ludwig W, Whitman WB, editor. New York: Springer; 2011. Genus XXXIX. Ornithobacterium Vandamme, Segers, Vancanneyt, Van Hove, Mutters, Hommez, Dewhirst, Paster, Kersters, Falsen, Devriese, Bisgaard, Hinz and Mannheim 1994b, 2011, 35VP: 250–4 [8] John, R. Glisson. Bacterial Respiratory Diseases of Poultry. Poultry Science, 1998, 77: 1139-1142. [9] Marien M, Decostere A, Martel A, Chiers K, Froyman R, Nauwynck H.. Synergy between avian pneumovirus and Ornithobacterium rhinotracheale in turkeys. Avian Pathol. 2005, 34(3): 204-11. [10] Nguyen, H. B. & Tran, H. T. L.. Giao trinh Mien Dich Hoc Ung Dung. Ha Noi, Viet Nam: NXB Nong Nghiep, 2007. [11] Numee, S., Hauck, R., Hafez, H. M.. Detection and typing of Ornithobacterium rhinotracheale from German poultry flocks. Avian Disease, 2012, 56(4): 654-8 [12] Peter De Herdt, Katty Cauwerts, Jan Vervloesem and Richard Ducatelle.. The relevance and efficacy of Ornithobacterium rhinotracheale control in chickens. World Poultry - Elsevier, 2001, 17(10): 01 [13] Rodrigo, A. E.. Bacterin Usage - Ross note, 2016. Retrieved November 2016, from: http://en.aviagen.com/assets/Tech_Center/Ross_Tech_Articles/RossNote-BacterinUsage-2016-EN.pdf [14] Schuijffel, D. F., van Empel, P. C. M., Pennings, A. M. M. A., van Putten, J.P.M., & Nuijten, P. J. M.. Successful Selection of Cross-Protective Vaccine Candidates for Ornithobacterium rhinotracheale Infection. Infection and Immunity, 2005, 73: 6812-6821. [15] Umali, D. V., Shirota, K., Sasai, K., & Katoh, H.. Characterization of Ornithobacterium rhinotracheale from commercial layer chickens in eastern Japan. Poultry Science, 2018, 97: 24-29. [16] Van Empel, P.C.M., Hafez, H.M.. Ornithobacterium rhinotracheale:a review. Avian Pathology, 1999, 28: 217-227. [17] Vo, N. C., Dinh, T. T. P., Bui, D. H., Nguyen, H. M., Vo, H. X., Le, H. T. & Quach, A. T. National conference animal and veterinary sciences. Surverying the disease situation. economic loss, prevention and treatment regimen for Ornithobacterium rhinotracheale (ORT) in chickens in the south of Vietnam. Ho Chi Minh, Viet Nam: NXB Nong Nghiep, 2019.