Clinical Characteristics and Risk Factors of Atrial Fibrillation in the Elderly
Source: By:Hong Li
DOI: https://doi.org/10.30564/jgm.v1i01.735
Abstract:Objective: To investigate the epidemiobgical characteristics of the elderly with atrial fibrillation (AF) in age, gender, the types of AF and relative causes. And To analyze the risk factors of persistent AF (PeAF), then use them to guide to prevent and treat for AF in the elderly.Methods: Collect the data of elderly patients with AF who were admitted to Liaoning People's Hospital from September 1, 2016 to September 30, 2017, and summarize the epidemiological characteristics of AF in the elderly. The risk factors for PeAF were analyzed by Spearman correlation analysis and mltivariate logistic regression analysis. Result: 1. In the elderly, the number of AF cases increase with age. The group of 75-84 years old was the largest part. The number of older females was larger than male in all ages. It was important to pay more attention to old woman with AF. 2.In the elderly, nonvalvular atrial fibrillation is popular. The top three causes of AF in the elderly were CHD, hypertension and heart failure. In the elderly, comorbidities were frequent, and the management was a major therapeutic objective. 3.CRP, 1eft atria diameter were the independent risk factors for PeAF in the elderly.
References:[1] Chugh S S, Havmoeller R Narayanan K, et a1. Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study[J]. Circulation, 2014, 129(8): 837-847. [2] Miyasaka Y, Barnes M E, Gersh B J, et a1. Secular trends in incidence of atrial fibrillation in OImsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence [J]. Circulation, 2006, 114(2): 119-125. [3] Go A S, Hylek E M, Phillips K A, et a1. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: The Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA)Study [J]. Jama, 2001, 285(18): 2370. [4] Krijthe B P, Kunst A, Benjamin E J, et a1. Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060[J]. European Heart Journal, 2013, 34(35): 2746-51. [5] Chiang C E, Wang K L, Lip G Y. Stroke prevention in atrial fibrillation: an Asian perspective[J]. Thromb Haemost, 2014, 111(5): 789-97. [6] Kannel W B, Abbott R D, Savage D D, et a1. Epidemiologic features of chronic atrial fibrillation: the Framingham study [J]. New England Journal of Medicine, 1982, 306(17): 1018. [7] Ziqiang Zhou, Dayi Hu, Jie Chen, et al. Epidemiological study on the current status of atrial fibrillation in China [J]. Chinese Journal of Internal Medicine, 2004, 43(7): 491-494. [8] Stewart S, Hart C L, Hole D J, et al. A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up of the Renfrew/Paisley study[J]. American Journal of Medicine, 2002, 113(5): 359-364. [9] Rich M W, Chyun D A, Skolnick A H, et a1. Knowledge Gaps in Cardiovascular Care of the Older Adult Population: A Scientific Statement from the American Heart Association, American College of Cardiology, and American Geriatrics Society[J]. Journal of the American College of Cardiology, 2016, 67(20): 2419-2440. [10] Chinese Experts'Suggestions on the Diagnosis and Treatment of Atrial Fibrillation in the Elderly (2011) [J]. Chinese Journal of Practical Internal Medicine, 2012, 30(4): 894-908. [11] Carom A J, Kirchhof P, Lip G Y H, et al. Guidelines for the management of atrial fibrillation The Task Force for the Management of Atrial F1brillation of the European Society of Cardiology (ESC)[M]//European Heart Journal. 2010: 2369-2429. [12] Hanon O, Assayag P, Belmin J, et a1. Expert consensus of the French Society of geriatrics and gerontology and the French society of cardiology on the management of atrial fibrillation in elderly people [J]. Archives of Cardiovascular Diseases, 2013, 106(5): 303-23. [13] Chinese Society of Cardiovascular Diseases of Chinese Medical Association. Retrospective investigation of hospitalized cases of atrial fibrillation in parts of China [J]. Chinese Journal of Cardiology, 2003, 31(12): 913-916. [14] Yanjun Gong, Wenhui Ding, Yansheng Ding, et al. Analysis of etiology (or related factors) in 1335 patients with atrial fibrillation [J]. Chinese Journal of Geriatric Heart Brain and Vessel Diseases. 2006, 8(10): 658-661. [15] Feinberg W M, Blackshear J L, Laupacis A, et al. Prevalence, age distribution gender of patients with atrial fibrillation. Analysis and implications [J]. Archives of Internal Medicine, 1995, 155(5): 469. [16] Fang M C, Singer D E, Chang Y et a1. Gender differences in the risk of ischemic stroke and peripheral embolism in atrial fibrillation: The AnTicoagulation and Risk factors In Atrial fibrillation (ATRIA)study [J]. Circulation, 2005, 112(12): 1687-1691. [17] Andersson T, Magnuson A, Bryngelsson I L, et a1. All-cause mortality in 272186 patients hospitalized with incident atrial fibrillation 1995~2008: a Swedish nationwide long-term case-control study[J]. European Heart Journal, 2013, 34(14): 1061. [18] Guo Y, Tian Y, Wang H, et a1. Prevalence, incidence, and lifetime risk of atrial fibrillation in China: new insights into the global burden of atrial fibrillation[J]. Chest, 2015, 147(1): 109-119. [19] Chugh S S, Havmoeller R, Narayanan K, et al. Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study [J]. Circulation, 2014, 129(8): 837-47. [20] Ko D, Rahman F, Schnabel R B, et a1. Atrial fibrillation in women: epidemiology, pathophysiology, presentation and prognosis[J]. Nature Reviews Cardiology, 2016, 13(6): 321. [21] Ning Wang, Mingzhao Qin, Current status of treatment of female nonvalvular atrial fibrillation [J]. Chinese Journal of Geriatric Heart Brain and Vessel Diseases, 2018(1): 99-101. [22] Chinese expert consensus on diagnosis and treatment of chronic heart failure combined with atrial fibrillation. Chinese Journal of Medicine, 2011, 46: 78-84. [23] Wentao Ma, Xiaohan Fan, Shu Zhang, Therapeutic development direction of atrial fibrillation complicated with heart failure [J]. Chinese Circulation Journal, 2016, 31(11): 1142-1144. [24] O’Neal W T, Soliman E Z, Qureshi W, et a1. Sustained pre-hypertensive blood pressure and incident atrial fibrillation: The Multi-Ethnic Study of Atherosclerosis[J]. Journal of the American Society of Hypertension Jash, 2015, 9(3): 191-196. [25] Cohen D, Tedrow UB, Koplan BA, et a1. Influence of systolic and diastolic blood pressure on the risk of incident atrial fibrillation in women. Circulation 2009; 119: 2146-52. [26] Grundvold I, Skretteberg PT, LiestM K, et a1. Upper normal blood pressures predict incident atrial fibrillation in healthy middle-aged men: a 35-year follow-up study. Hypertension 2012; 59: 198-204. [27] Michell GF, Vasan RS, Keyes MJ, et a1. Pulse pressure and risk of new-onset atrial fibrillation. JAMA 2007; 297: 709-15. [28] Wenqing Lei, Correlation between circadian rhythm of blood pressure and paroxysmal atrial fibrillation in elderly hypertensive patients [J]. Chinese Journal of Geriatric Care, 2016, 14(1): 16-20. [29] Webb AJ, Rothwell PM. Blood pressure variability and risk of new-onset atrial fibrillation: a systematic review of randomized trials of antihypertensive drugs [J]. Stroke, 2010, 41(9): 2091-2093.