Comparative Analysis of Steel Plates and PLA Used for Joint Repair in Humans and Canines

Source:
By:Yi Zhu, Yibo Wang, Fan Yang, Hao Yue

DOI: https://doi.org/10.30564/jim.v10i1.2755

Abstract:

The exploration of fracture internal fixation materials has been one of the research hotspots in the field of biomedical materials. The traditional internal fixation material for fracture is metal fixation. Although its mechanical strength is very large, it can not be degraded and absorbed in human body after implantation of human body or canine joint, which requires a secondary operation to remove, which not only brings pain to patients, but also causes economic pay.[1] Therefore, the development of a biodegradable fracture internal fixation material has become the goal of many researchers. Polylactic acid (PLA) is nontoxic and harmless, has good biocompatibility and strong mechanical properties. It can be degraded in vivo after implantation. The degradation products are CO2 and H2O.[2] For the study of the feasibility of polylactic acid as a substitute for common fracture fixation materials ,18 northern Chinese pastoral dogs were randomly divided into blank group, PLA group and plate group. The data were recorded according to the Wakitani score from the first week to the fifteenth week after operation. First, all the indexes were divided into two categories by principal component analysis [3], then the blank group, steel plate group and PLA group were fitted and compared. Finally, it is concluded that PLA is more beneficial to joint repair than steel plate.

References:

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