A Meta-analysis of Acupuncture Treatment for Irritable Bowel Syndrome

Updata:01-01-1970

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By:Changzhen Gong

DOI: https://doi.org/10.30564/jim.v10i2.3373

Abstract:
To assess the efficacy of acupuncture for treatment of irritable bowel syndrome through meta-analysis of randomized controlled trials in recent 20 years. Online databases, including CNKI, VIP, WANFANG,PubMed, Cochrane Library, Web of Science and Embase were searched for randomized controlled trials (RCTs) of acupuncture for IBS. Retrieval time was from January 1, 2000 to January 31, 2021. According to Jadad scoring criteria,the bias risk and quality assessment of each RCT included were evaluated by two researchers. RevMan 5.3 software was used for the meta analysis. Eight RCTs were selected which include a total of 1181 patients.The control group has 425 patients and the experimental group has 756 patients. The result of meta-analysis indicates that the total effective rate for the experimental group was superior to that of the control group [OR=3.29,95%CI [2.16~5.03](P<0.01)], and the funnel plot was basically symmetric. Acupuncture therapy is shown to have a good safety and compliance record. However, the number of high-quality trials is small, and there are some deficiencies in the methodology of clinical research. Acupuncture, as a supplementary therapy for irritable bowel syndrome, has positive clinical significance and prospects for application. The methodology of clinical research needs to be further improved.
References:

[1]Chen Liping, Wang Shijun, Lu yan, etc. Research Progress on Acupuncture Treatment for IBS-D[J]. Shandong Journal of Traditional Chinese Medicine, 2015，34(01),71-73. [2]Guo jing, Sun Jianhua, Chen Lu, etc. Correlation between curative effect and 5-HTTLPR polymorphism in treatment of diarrhea-predominant irritable bowel syndrome with acupuncture for regulating shen and strengthening pi[J/OL]. Chinese Acupuncture & Moxibustion. [3]Wang Shanshan, Wang Xurui, Yangyong, etc. Efficacy and mechanism of acupuncture combined with Tongxieyaofang for diarrhea-typeirritable bowel syndrome of liver depression and spleen deficiency[J]. Chinese Acupuncture & Moxibustion, 2020,40(06),605-609. [4]Wang Qian, Chen Kaijun, Yu Ansheng. Therapeutic effects and mechanism of acupuncture on hepatic spleen deficiency and irritable bowel syndrome[J].Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2019,27(07),520-524. [5]Pei Lixia,Chen Hao,Guo Jing, etc. Effect of acupuncture and its influence on visceral hypersensitivity in IBS-D patients: Study protocol for a randomized controlled trial[J]. Medicine (Baltimore)，2018, 97 (21): 10877. [6] Li Jing, Lu Jin, Sun Jianhua, etc. Acupuncture with regulating mind and spleen for diarrhea irritable bowel syndrome and sleep quality:a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2017,37(01),9-13. [7]Hui Zheng, Ying Li, Wei Zhang，etc. Electroacupuncture for patients with diarrhea-predominant irritable bowel syndrome or functional diarrhea: A randomized controlled trial[J]. Medicine (Baltimore), 2016, 95 (24): 3884. [8]Qian Huohui, Zhu Yongping, Meng Shan, etc.Acupuncture treatment of diarrhea-predominant irritable bowel syndrome: a randomized controlled trial[J]. World Chinese Journal of Digestology, 2011, 19(3): 257-261. [9]Alastair Forbes，Sue Jackson，Clare Walter，etc. Acupuncture for irritable bowel syndrome: A blinded placebo-controlled trial[J]. World J Gastroenterol, 2005, 11(26): 4040-4044.

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